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Neumig 5mg Tablet
Mirogabalin Besylate is indicated for the treatment of- Neuropathic Pain, Diabetic peripheral neuropathic pain (DPNP), Postherpetic neuralgia (PHN), Peripheral neuropathic pain (PNP)
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✅ Description:
Mirogabalin binds selectively to α2δ subunits of voltage-gated calcium channels (VGCCs), reducing calcium influx and neurotransmitter release in neurons. This action alleviates neuropathic pain by modulating hyperactive neural circuits.
This medication is a significant option for patients suffering from chronic neuropathic pain but must be used under close medical supervision.
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✔️ Side Effects: Neumig 5
Common:
- Somnolence
- Dizziness
- Edema (swelling)
- Weight gain
Rare but serious:
- Liver Dysfunction: Symptoms include jaundice, nausea, vomiting, and general malaise.
- Severe CNS Effects: Light-headedness, loss of consciousness, or near-unconscious states.
✔️ Indications: Neumig 5
Mirogabalin, a gabapentinoid, is prescribed for managing neuropathic pain, including:
- Diabetic peripheral neuropathy (DPNP)
- Postherpetic neuralgia (PHN)
- Peripheral neuropathic pain (PNP)
✔️ Drug Interactions: Neumig 5
- Alcohol & CNS Depressants (e.g., Lorazepam): Enhanced sedative effects.
- Cimetidine & Probenecid: May increase plasma concentrations of Mirogabalin.
✔️ Contraindications: Neumig 5
- Hypersensitivity to Mirogabalin or any formulation components.
- Mild to moderate hepatic and renal impairment.
✔️ Dosage & Administration: Neumig 5
- Initial Dose: 5 mg orally, twice daily.
- Titration: Gradual increments of 5 mg at weekly intervals, up to 15 mg twice daily.
- Maintenance Dose: Between 10 mg and 15 mg twice daily, based on age and symptom severity.
- Always take the medication as directed by your physician.
✔️ Precautions & Warnings
- Alcohol Use: Avoid consuming alcohol, as Mirogabalin can cause excessive drowsiness and CNS depression.
- Driving/Operating Machinery: This drug may impair alertness, and cause drowsiness, dizziness, or blurred vision. Avoid such activities if symptoms occur.
- Kidney Impairment: Caution is advised; dose adjustment may be necessary.
- Liver Impairment: No dose adjustment is required, making it safe for use in patients with liver disease.
- Elderly Patients: Special attention is required due to an increased risk of dizziness and somnolence.
✔️ Pregnancy & Lactation:
- Pregnancy: Limited safety data; consult your doctor.
- Lactation: Insufficient data on its excretion in breast milk; consult your doctor before use.
✔️ Storage:
- Store below 30°C in a dry place, away from light and moisture.
- Keep out of the reach of children.
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